Reproduction Abstracts

Inhibin is a heterodimeric gonadal glycoprotein hormone belonging to the TGFβ superfamily that named for its ability to suppress FSH synthesis and secretion from anterior pituitary via a negative feedback. It can regulate proliferation, differentiation, and steroidogenesis of granulosa cells (GCs) through paracrine and autocrine manners. The objective of this study was to investigate the interaction between inhibin α subunit (INHA) and apoptosis of porcine ovarian GC...

Introduction: Phosphoinositide 3-kinase (PI3K) activity has been reported to be critical to sperm motility and mitochondrial ROS generation while mitochondrial membrane protein Prohibitin (PHB) controls PI3K/AKT pathway in somatic cells by regulating mitochondrial function. Our recent findings showed that sperm PHB expression is significantly decreased in infertile men with poor sperm quality by regulating mitochondrial morphology and function. The objective of this study is t...